Jacob's Syndrom

Jacob’s Syndrome

Jacob’s Syndrome is a rare chromosomal genetic syndrome where the male has an

extra Y male chromosome and ends up having 47 chromosomes with XYY instead of

normal 46,XY (male) or 46, XX (female.) It is very rare and happens in only

about 1 out of 1,000 men. The exact reason for this is unknown. In a very rare cases it was passed from father to son, but in most cases it is not hereditary. It was first

discovered by Patricia Jacobs in 1965. She proposed the suggestion that the

extra Y chromosome might lead to increased aggression in these men and might

land them in trouble with the law.

Usually this chromosomal change doesn’t cause any unusual physical features or

medical problems. 47,XYY boys and men are usually taller than average and

about seven centimeters taller than their parents and siblings. Bad acne was

noticed in very few early case reports, but dermatologists specializing in acne

now doubt that there's any relation between the two. Boys with XYY are usually normally

developed at birth with normal birth weight and length without any abnormal physical features.

Boys with XYY are often more physically active than their brothers, and if

this activity is accepted, sports and other physical activities together with

the parents and together with other children isn’t bad in any way. These boys are usually slow at developing emotional maturity, and this sometimes

leads to to learning problems in school.

It's really important